The M6 in Lancashire closed northbound between J32 and J33 after the accident. National Highways is suggesting a diversion route, urging drivers to avoid the road and find alternative routes.
Emergency services taken at the scene to assist.
It is still unknown if anyone was injured from the accident.
According to National Highways. the delay is currently estimated at 90 minutes.
The congestion on the M6 has reached 8 miles.
The service said that, because of the accident, a large amount of diesel and oil has spilled onto the carriageway.
They added: “This will need to be cleared and the road surface inspected for damage.”
National Highways is suggesting the following diversion route:
“Road users are advised to follow the hollow circle diversion symbols on road signs.
- Exit M6 J32 (Blackpool), onto M55
- Follow M55 westbound to J1 Exit M55 at J1 (Broughton) and take third roundabout exit, A6 Garstang
- Follow A6 northbound through Broughton, Barton, Bilsborrow, Garstang, to M6 J33 (Lancaster South), rejoin M6 northbound”