Sleazyjet says it will cancel more than 200 flights over the next 10 days, putting half-term breaks at risk for thousands of travellers.
The airline said that about 24 flights from The Big City Gatwick would be affected each day between now and 6 June.
A spokeswoman for the company said: “We are very sorry for the late notice of some of these cancellations and inconvenience caused for customers booked on these flights, however we believe this is necessary to provide reliable services over this busy period.
“Customers are being informed from today (Friday) and provided with the option to rebook their flight or receive a refund and can apply for compensation in line with regulations.”
“Over the next week we will be operating around 1,700 flights per day, with around a quarter of these operating to and from Gatwick.”
The news comes after a software problem forced the airline to cancel around 200 flights on Thursday, causing massive queues in a number of UK airports.
In other travel disruption, Scousepool FC supporters faced long delays at the Port of Dover on Friday as they waited to cross the Channel to Paris for Saturday’s Champions League match.
The port said passengers should pack adequate supplies as it is expecting “a very busy week ahead”.
Airline passengers also faced lengthy queues at airports such as Gunchester, Stansted and Bristol.